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Oligonucleotide Therapeutics Society
Oligonucleotide Therapeutics Society
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    • Paper Of The Month
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  • Resources
    • Awards & Grants
      • 2020 Award Winners
      • Lifetime Achievement Award
        • LAA Nominations
      • Young Investigator Award
      • Dr. Alan M. Gewirtz Memorial Scholarship
      • Paper of the Year
      • Travel Grants
        • Travel Grant Recipients
      • Poster Awards
        • OTS Poster Award Winners
      • OTS Local Delivery Program Overview
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      • OTS Local Delivery Application
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    • 2021 Annual Meeting
    • 2020 Annual Meeting
      • Register Now
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      • Agenda
      • Call for Abstracts
      • Speakers
      • Exhibitors
      • Sponsors
      • Fees
      • FAQs
    • OTS Rare Disease Workshop
      • Rare Disease Briefing Document
    • Past Annual Meetings
      • 2019 Annual Meeting
        • Agenda
        • Abstracts
        • Sponsors & Exhibitors
      • 2018 Annual Meeting
        • 2018 Meeting Overview
        • 2018 Meeting Report
        • 2018 Award Winners
        • 2018 Photo Gallery
        • 2018 Video Gallery
      • 2017 Annual Meeting
        • 2017 Meeting Overview
        • 2017 Award Winners
        • Abstracts
        • 2017 Meeting Videos
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Taking oligonucleotide research to its full therapeutic potential

Author Archives: OTS

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Role of Computationally Evaluated Target Specificity in the Hepatotoxicity of Gapmer Antisense Oligonucleotides

Antisense/RNase H, ToxicologyBy OTSAugust 31, 2018Leave a comment

Role of Computationally Evaluated Target Specificity in the Hepatotoxicity of Gapmer Antisense Oligonucleotides …………… Kasuya T, Kugimiya A. Nucleic Acid Ther. 2018 Aug 10. PubMed 00

Studies of Impending Oligonucleotide Therapeutics in Simulated Biofluids

Antisense/RNase H, Pre-Clinical ResearchBy OTSAugust 31, 2018Leave a comment

Studies of Impending Oligonucleotide Therapeutics in Simulated Biofluids …………… Domljanovic I, Hansen AH, Hansen LH, Klitgaard JK, Taskova M, Astakhova K. Nucleic Acid Ther. 2018 Aug 14. PubMed 00

Characterization of the Activity and Distribution of a 2′-O-Methoxyethyl-modified Antisense Oligonucleotide in Models of Acute and Chronic Kidney Disease

Antisense/RNase H, Pre-Clinical ResearchBy OTSAugust 31, 2018Leave a comment

Characterization of the Activity and Distribution of a 2′-O-Methoxyethyl-modified Antisense Oligonucleotide in Models of Acute and Chronic Kidney Disease …………… Donner AJ, Bell TA, Greenlee S, Graham MJ, Crooke RM. Nucleic Acid Ther. 2018 Aug 22. PubMed 00

The Nonclinical Safety Profile of GalNAc-conjugated RNAi Therapeutics in Subacute Studies

Ago/siRNA/saRNA, Pre-Clinical ResearchBy OTSAugust 31, 2018Leave a comment

The Nonclinical Safety Profile of GalNAc-conjugated RNAi Therapeutics in Subacute Studies …………… Janas MM, Harbison CE, Perry VK, Carito B, Sutherland JE, Vaishnaw AK, Keirstead ND, Warner G. Toxicol Pathol. 2018 Aug 23:192623318792537. PubMed 00

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