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Oligonucleotide Therapeutics Society
Oligonucleotide Therapeutics Society
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      • Rare Disease Briefing Document
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      • 2019 Annual Meeting
        • Agenda
        • Abstracts
        • Sponsors & Exhibitors
      • 2018 Annual Meeting
        • 2018 Meeting Overview
        • 2018 Meeting Report
        • 2018 Award Winners
        • 2018 Photo Gallery
        • 2018 Video Gallery
      • 2017 Annual Meeting
        • 2017 Meeting Overview
        • 2017 Award Winners
        • Abstracts
        • 2017 Meeting Videos
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Taking oligonucleotide research to its full therapeutic potential

Author Archives: OTS

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In utero CRISPR-mediated therapeutic editing of metabolic genes

Gene editingBy OTSOctober 31, 2018Leave a comment

In utero CRISPR-mediated therapeutic editing of metabolic genes …………… Rossidis AC, Stratigis JD, Chadwick AC, Hartman HA, Ahn NJ, Li H, Singh K, Coons BE, Li L, Lv W, Zoltick PW, Alapati D, Zacharias W, Jain R, Morrisey EE, Musunuru K, Peranteau WH. Nat Med. 2018 Oct;24(10):1513-1518. PubMed 00

Genetic Modulation of RNA Splicing with a CRISPR-Guided Cytidine Deaminase

Alternative splicing, Gene editingBy OTSOctober 31, 2018Leave a comment

Genetic Modulation of RNA Splicing with a CRISPR-Guided Cytidine Deaminase …………… Yuan J, Ma Y, Huang T, Chen Y, Peng Y, Li B, Li J, Zhang Y, Song B, Sun X, Ding Q, Song Y, Chang X. Mol Cell. 2018 Oct 18;72(2):380-394.e7. PubMed 00

Several structural motifs cooperate in determining the highly effective anti-thrombin activity of NU172 aptamer

AptamerBy OTSOctober 31, 2018Leave a comment

Several structural motifs cooperate in determining the highly effective anti-thrombin activity of NU172 aptamer …………… Troisi R, Napolitano V, Spiridonova V, Russo Krauss I, Sica F. Nucleic Acids Res. 2018 Oct 24. PubMed 00

Osteopontin mediates glioblastoma-associated macrophage infiltration and is a therapeutic target

AptamerBy OTSOctober 31, 2018Leave a comment

Osteopontin mediates glioblastoma-associated macrophage infiltration and is a therapeutic target …………… Wei J, Marisetty A, Schrand B, Gabrusiewicz K, Hashimoto Y, Ott M, Grami Z, Kong LY, Ling X, Caruso HG, Zhou S, Wang YA, Fuller GN, Huse JT, Gilboa E, Kang N, Huang X, Verhaak R, Li S, Heimberger AB. J Clin Invest. 2018…

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