Interview with Julia Alterman
Julia Alterman, PhD RNA Therapeutics Institute, University of Massachusetts Medical School How did you become interested in the field of oligonucleotides? After finishing my bachelor’s degree at the University of Vermont I started my scientific career in the vibrant Boston biotech community. My first ...
Clinical Pharmacology Studies Supporting Oligonucleotide Therapy Development: An Assessment of Therapies Approved and in Development Between 2012-2018
Rogers H, Adeniyi O, Ramamoorthy A, Bailey S, Pacanowski M. Clin Transl Sci. 2020 Dec 5. Pubmed
RNA structure-wide discovery of functional interactions with multiplexed RNA motif library
Komatsu KR, Taya T, Matsumoto S, Miyashita E, Kashida S, Saito H. Nat Commun. 2020 Dec 8;11(1):6275. Pubmed
Functional Atlas of Primary miRNA Maturation by the Microprocessor
Rice GM, Shivashankar V, Ma EJ, Baryza JL, Nutiu R. Mol Cell. 2020 Dec 3;80(5):892-902.e4. Pubmed
Screening for functional circular RNAs using the CRISPR-Cas13 system
Li S, Li X, Xue W, Zhang L, Yang LZ, Cao SM, Lei YN, Liu CX, Guo SK, Shan L, Wu M, Tao X, Zhang JL, Gao X, Zhang J, Wei J, Li J, Yang L, Chen LL. Nat Methods. Epub 2020 Dec 7. Pubmed ...
Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine
Polack FP, Thomas SJ, Kitchin N, Absalon J, Gurtman A, Lockhart S, Perez JL, Pérez Marc G, Moreira ED, Zerbini C, Bailey R, Swanson KA, Roychoudhury S, Koury K, Li P, Kalina WV, Cooper D, Frenck RW Jr, Hammitt LL, Türeci Ö, Nell H, Schaefer ...
Safety and Immunogenicity of SARS-CoV-2 mRNA-1273 Vaccine in Older Adults
Anderson EJ, Rouphael NG, Widge AT, Jackson LA, Roberts PC, Makhene M, Chappell JD, Denison MR, Stevens LJ, Pruijssers AJ, McDermott AB, Flach B, Lin BC, Doria-Rose NA, O'Dell S, Schmidt SD, Corbett KS, Swanson PA 2nd, Padilla M, Neuzil KM, Bennett H, Leav B, ...
Ligand conjugated antisense oligonucleotide for the treatment of transthyretin amyloidosis: preclinical and phase 1 data
Viney NJ, Guo S, Tai LJ, Baker BF, Aghajan M, Jung SW, Yu RZ, Booten S, Murray H, Machemer T, Burel S, Murray S, Buchele G, Tsimikas S, Schneider E, Geary RS, Benson MD, Monia BP. ESC Heart Fail. 2020 Dec 7. Pubmed ...
Post-Transcriptional Genetic Silencing of BCL11A to Treat Sickle Cell Disease
Esrick EB, Lehmann LE, Biffi A, Achebe M, Brendel C, Ciuculescu MF, Daley H, MacKinnon B, Morris E, Federico A, Abriss D, Boardman K, Khelladi R, Shaw K, Negre H, Negre O, Nikiforow S, Ritz J, Pai SY, London WB, Dansereau C, Heeney MM, ...
Double Controlled Release of Therapeutic RNA Modules through Injectable DNA-RNA Hybrid Hydrogel
Han S, Park Y, Kim H, Nam H, Ko O, Lee JB. ACS Appl Mater Interfaces. 2020 Dec 16;12(50):55554-55563. Pubmed
