Base editors for simultaneous introduction of C-to-T and A-to-G mutations.
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Combinatorial Inhibition of Cell Surface Receptors Using Dual Aptamer-Functionalized Nanoconstructs for Cancer Treatment.
Lee H, Kim TH, Park D, Jang M, Chung JJ, Kim SH, Kim SH, Lee KH, Jung Y, Oh SJ. Pharmaceutics. 2020 Jul 21;12(7):E689. Pubmed
Genome editing with CRISPR-Cas nucleases, base editors, transposases and prime editors.
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Accelerated cryo-EM-guided determination of three-dimensional RNA-only structures.
Kappel K, Zhang K, Su Z, Watkins AM, Kladwang W, Li S, Pintilie G, Topkar VV, Rangan R, Zheludev IN, Yesselman JD, Chiu W, Das R. Nat Methods. 2020 Jul;17(7):699-707. Pubmed
Cell-free biosensors for rapid detection of water contaminants.
Jung JK, Alam KK, Verosloff MS, Capdevila DA, Desmau M, Clauer PR, Lee JW, Nguyen PQ, Pastén PA, Matiasek SJ, Gaillard JF, Giedroc DP, Collins JJ, Lucks JB. Nat Biotechnol. 2020 Jul 6. Pubmed
Functional annotation of human long noncoding RNAs via molecular phenotyping.
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Impact of mRNA chemistry and manufacturing process on innate immune activation.
Nelson J, Sorensen EW, Mintri S, Rabideau AE, Zheng W, Besin G, Khatwani N, Su SV, Miracco EJ, Issa WJ, Hoge S, Stanton MG, Joyal JL. Sci Adv. 2020 Jun 24;6(26):eaaz6893. Pubmed
An mRNA Vaccine against SARS-CoV-2 – Preliminary Report.
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An RNA vaccine drives immunity in checkpoint-inhibitor-treated melanoma.
Sahin U, Oehm P, Derhovanessian E, Jabulowsky RA, Vormehr M, Gold M, Maurus D, Schwarck-Kokarakis D, Kuhn AN, Omokoko T, Kranz LM, Diken M, Kreiter S, Haas H, Attig S, Rae R, Cuk K, Kemmer-BrĂ¼ck A, Breitkreuz A, Tolliver C, Caspar J, Quinkhardt J, Hebich ...
Efficiency and Target Derepression of Anti-miR-92a: Results of a First in Human Study.
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