RNA-Seq Analysis of an Antisense Sequence Optimized for Exon Skipping in Duchenne Patients Reveals No Off-Target Effect
Domenger C, Allais M, François V, Léger A, Lecomte E, Montus M, Servais L, Voit T, Moullier P, Audic Y, Le Guiner C. MolTher Nucleic Acids. 2018 Mar 2;10:277-291. PubMed
Relationship between “LDL-C”, estimated true LDL-C, apolipoprotein B-100, and PCSK9 levels following lipoprotein(a) lowering with an antisense oligonucleotide
Viney NJ, Yeang C, Yang X, Xia S, Witztum JL, Tsimikas S. J ClinLipidol. 2018 Mar 1. pii: S1933-2874(18)30065-5. PubMed
Direct Selection of Fluorescence-Enhancing RNA Aptamers
Gotrik M, Sekhon G, Saurabh S, Nakamoto M, Eisenstein M, Soh HT. J Am Chem Soc. 2018 Mar 14;140(10):3583-3591. PubMed
Prevention of Asthma Exacerbation in a Mouse Model by Simultaneous Inhibition of NF-κB and STAT6 Activation Using a Chimeric Decoy Strategy
Miyake T, Miyake T, Sakaguchi M, Nankai H, Nakazawa T, Morishita R. MolTher Nucleic Acids. 2018 Mar 2;10:159-169. PubMed
Poly-ligand profiling differentiates trastuzumab-treated breast cancer patients according to their outcomes
Domenyuk V, Gatalica Z, Santhanam R, Wei X, Stark A, Kennedy P, Toussaint B, Levenberg S, Wang J, Xiao N, Greil R, Rinnerthaler G, Gampenrieder SP, Heimberger AB, Berry DA, Barker A, Quackenbush J, Marshall JL, Poste G, Vacirca JL, Vidal GA, Schwartzberg LS, Halbert ...
Systematic Discovery of RNA Binding Proteins that Regulate MicroRNA Levels
Nussbacher JK, Yeo GW. Mol Cell. 2018 Mar 15;69(6):1005-1016.e7. PubMed
Pervasive Regulatory Functions of mRNA Structure Revealed by High-Resolution SHAPE Probing
Mustoe AM, Busan S, Rice GM, Hajdin CE, Peterson BK, Ruda VM, Kubica N, Nutiu R, Baryza JL, Weeks KM. Cell. 2018 Mar 22;173(1):181-195.e18. PubMed
TargetedmRNATherapy for Ornithine Transcarbamylase Deficiency
Prieve MG, Harvie P, Monahan SD, Roy D, Li AG, Blevins TL, Paschal AE, Waldheim M, Bell EC, Galperin A, Ella-Menye JR, Houston ME. MolTher. 2018 Mar 7;26(3):801-813. PubMed
Innate Immune Response and Off-Target Mis-splicing Are Common Morpholino-Induced Side Effects in Xenopus
Gentsch GE, Spruce T, Monteiro RS, Owens NDL, Martin SR, Smith JC. Dev Cell. 2018 Mar 12;44(5):597-610.e10. PubMed
Non-coding RNAs as therapeutic targets for preventing myocardial ischemia-reperfusion injury
Ong SB, Katwadi K, Kwek XY, Ismail NI, Chinda K, Ong SG, Hausenloy DJ. Expert OpinTher Targets. 2018 Mar;22(3):247-261. PubMed