Cryptotanshinone Protects Cartilage against Developing Osteoarthritis through the miR-106a-5p/GLIS3 Axis
Ji Q, Qi D, Xu X, Xu Y, Goodman SB, Kang L, Song Q, Fan Z, Maloney WJ, Wang Y. Mol Ther Nucleic Acids. 2018 Jun 1;11:170-179. PubMed
miR-23b and miR-218 silencing increase Muscleblind-like expression and alleviate myotonic dystrophy phenotypes in mammalian models
Cerro-Herreros E, Sabater-Arcis M, Fernandez-Costa JM, Moreno N, Perez-Alonso M, Llamusi B, Artero R. Nat Commun. 2018 Jun 26;9(1):2482. PubMed
MicroRNA-351-5p aggravates intestinal ischemia/reperfusion injury via targeting MAPK13 and Sirt6
Hu Y, Tao X, Han X, Xu L, Yin L, Sun H, Qi Y, Xu Y, Peng J. Br J Pharmacol. 2018 Jun 27. PubMed
Effects of microRNA-292-5p on myocardial ischemia-reperfusion injury through the peroxisome proliferator-activated receptor-α/-γ signaling pathway
Zhu ZD, Ye JY, Niu H, Ma YM, Fu XM, Xia ZH, Zhang X. Gene Ther. 2018 Jun;25(3):234-248. PubMed
Artificial miRNAs Reduce Human Mutant Huntingtin Throughout the Striatum in a Transgenic Sheep Model of Huntington’s Disease
Pfister EL, DiNardo N, Mondo E, Borel F, Conroy F, Fraser C, Gernoux G, Han X, Hu D, Johnson E, Kennington L, Liu P, Reid SJ, Sapp E, Vodicka P, Kuchel T, Morton AJ, Howland D, Moser R, Sena-Esteves M, Gao G, Mueller C, DiFiglia ...
RNA Structure Design Improves Activity and Specificity of trans-Splicing-Triggered Cell Death in a Suicide Gene Therapy Approach
Poddar S, Loh PS, Ooi ZH, Osman F, Eul J, Patzel V. Mol Ther Nucleic Acids. 2018 Jun 1;11:41-56. PubMed
Peptide-conjugated phosphodiamidate oligomer-mediated exon skipping has benefits for cardiac function in mdx and Cmah-/-mdx mouse models of Duchenne muscular dystrophy
Blain AM, Greally E, McClorey G, Manzano R, Betts CA, Godfrey C, O'Donovan L, Coursindel T, Gait MJ, Wood MJ, MacGowan GA, Straub VW. PLoS One. 2018 Jun 18;13(6):e0198897. PubMed
In vivo base editing of post-mitotic sensory cells
Yeh WH, Chiang H, Rees HA, Edge ASB, Liu DR. Nat Commun. 2018 Jun 5;9(1):2184. PubMed
Combination of aptamer and drug for reversible anticoagulation in cardiopulmonary bypass
Gunaratne R, Kumar S, Frederiksen JW, Stayrook S, Lohrmann JL, Perry K, Bompiani KM, Chabata CV, Thalji NK, Ho MD, Arepally G, Camire RM, Krishnaswamy S, Sullenger BA. Nat Biotechnol. 2018 Jun 4. PubMed
Modular cell-internalizing aptamer nanostructure enables targeted delivery of large functional RNAs in cancer cell lines
Porciani D, Cardwell LN, Tawiah KD, Alam KK, Lange MJ, Daniels MA, Burke DH. Nat Commun. 2018 Jun 11;9(1):2283. PubMed