2015 OTS Poster Award Winners

Umar Burki, Newcastle University –  Poster #009

In vivo Pharmacokinetic and Biodistribution profile of Peptide-Conjugated Phosphorodiamidate Morpholino Oligonucleotides

Alexandre Debacker, University of Southampton – Poster #020

Optimized DNA-PNA chimeras for silencing structured RNAs

Anna Dysko, University of Oxford – Poster #026

Synthesis of Modified Oligonucleotides Containing Triazole Backbones

Ellen Gyssels, University of Ghent – Poster #046

Covalently Locking Nucleic Acid Structures by the Inducible

Furan Cross-link Strategy: New Applications

Marcel Hollenstein, University of Bern – Poster #050

General compatibility of nucleoside triphosphates with rolling circle


Satish Jadhav, University of Turku – Poster #056

Synthesis of Carbohydrates/Bisphosphonate-Oligonucleotide Conjugates and their PET Imaging

Silvana Jirka, Leiden University Medical Center – Poster #057

¬Evaluation of 2’- deoxy-2’-fluoro antisense oligonucleotides for exon skipping in Duchenne muscular dystrophy

Yifat Oren, The Alexander Silberman Institute of Life Sciences – Poster #089

Restoration of cftr Function by Antisense Oligonucleotide Splicing Modulation

Maire Osborn, RNA Therapeutics Institute, UMass Medical School – Poster #090

A polyunsaturated fatty acid-siRNA conjugate targeting Huntingtin (Htt) mRNA shows prolonged efficacy, minimal toxicity, and broad distribution in mouse brain

Dina Polyak, Sackler School of Medicine Tel Aviv University – Poster #099

Hindering tumor growth by polymer-based targeted delivery of oligonucleotides

Jurriën Prins, Leiden University Medical Center – Poster #101

Post-Transcriptional Guidance of Monocyte to Macrophage Differentiation by the RNA-Binding Protein Quaking

Lodewijk Toonen, Leiden University Medical Center – Poster #118

Ataxin-3 exon skipping as a treatment strategy for Spinocerebellar Ataxia type 3

Tirsa Van Westering, University of Oxford – Poster #127

Cmah-/-mdx mouse early onset cardiac phenotype and correction of dystrophin by peptide-PMO for Duchenne muscular dystrophy

Ann Fiegen Durbin, Harvard University and MIT – Poster #144

Signal Interrupted: How RNAs containing modified nucleotides suppress RIG-I activation